SCHEMBL9322994

SCHEMBL9322994

CCCCCCCCCCC1CNC(=O)O1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.54
ALDH1A1 P00352 2/20 0.48
EPHX1 P07099 1/20 0.46
PPARG P37231 2/20 0.44
GRM2 Q14416 6/20 0.43
LMNA P02545 1/20 0.43
MAOA P21397 1/20 0.43
SLC6A2 P23975 1/20 0.43
PKM P14618 1/20 0.42
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9322761 1.00 CYP1A2 (0.54) CYP1A2ALDH1A1EPHX1PPARGGRM2
SCHEMBL2830202 1.00 CYP1A2 (0.54) CYP1A2ALDH1A1EPHX1PPARGGRM2
SCHEMBL5452024 0.92 LMNA (0.45) CYP1A2ALDH1A1PPARGGRM2LMNA
SCHEMBL5450456 0.86
SCHEMBL8396437 0.82 CYP1A2 (0.60) CYP1A2ALDH1A1EPHX1PPARGGRM2
Hexane SCHEMBL17769241 0.81 PTPN1 (0.43) CYP1A2ALDH1A1LMNAMAOASLC6A2
SCHEMBL18595269 0.78 LMNA (0.38) CYP1A2ALDH1A1LMNAMAOASLC6A2
SCHEMBL18595192 0.78 LMNA (0.38) CYP1A2ALDH1A1LMNAMAOASLC6A2
SCHEMBL8761955 0.78 ALDH1A1 (0.56) CYP1A2ALDH1A1LMNAMAOASLC6A2
SCHEMBL9324248 0.78 ALDH1A1 (0.56) CYP1A2ALDH1A1LMNAMAOASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0378657-B1 OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS RAJADHYAKSHA VITHAL J (US) 1994-02-02 EP claimed
US-4960771-A TRANSDERMAL DELIVERY OF THERAPEUTIC AGENTS; DRUGS, SUNSCREENS, INSECT REPELLENTS, COSMETICS LVMH MOET HENNESSY LOUIS VUITTON, INC. 1990-10-02 US claimed
EP-0378657-B1 OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS RAJADHYAKSHA VITHAL J (US) 1994-02-02 EP disclosed
US-4960771-A TRANSDERMAL DELIVERY OF THERAPEUTIC AGENTS; DRUGS, SUNSCREENS, INSECT REPELLENTS, COSMETICS LVMH MOET HENNESSY LOUIS VUITTON, INC. 1990-10-02 US disclosed
EP-0378657-A1 OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS. RAJADHYAKSHA VITHAL J 1990-07-25 EP disclosed
WO-1990000407-A1 OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS RAJADHYAKSHA VITHAL J (US) 1990-01-25 WO disclosed