SCHEMBL545211

SCHEMBL545211

C=CC[SiH2]OC(=O)C(C)C

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL496528 0.76
SCHEMBL704204 0.75 ELANE (0.30)
SCHEMBL704698 0.75 ELANE (0.30)
SCHEMBL5406669 0.75 TSHR (0.50) TSHR
SCHEMBL7758871 0.72 TSHR (0.34) TSHR
SCHEMBL170414 0.71
SCHEMBL123173 0.71
SCHEMBL5403242 0.71
SCHEMBL5398954 0.71
SCHEMBL5391575 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8110036-B2 Moisture curable oil and fat compositions and processes for preparing the same BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERISTY (US) 2012-02-07 US claimed
WO-2010042175-A1 MOISTURE-CURABLE OIL AND FAT COMPOSITIONS AND PROCESSES FOR PREPARING THE SAME MICHIGAN STATE UNIVERSITY (US) 2010-04-15 WO claimed
US-20100083871-A1 Moisture-curable oil and fat compositions and processes for preparing the same BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2010-04-08 US claimed
US-20070173935-A1 Nucleus pulposus augmentation pretreatment technique DEPUY SPINE, INC. 2007-07-26 US claimed
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2026-04-30 US disclosed
EP-4715465-A1 MULTILAYER BODY, METHOD FOR PRODUCING MULTILAYER BODY, AND PHOTOSENSITIVE SURFACE MODIFIER Nissan Chemical Corporation (JP) 2026-03-25 EP disclosed
US-12585188-B2 Composition for forming resist underlying film NISSAN CHEMICAL CORPORATION (JP) 2026-03-24 US disclosed
EP-4679175-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM Nissan Chemical Corporation (JP) 2026-01-14 EP disclosed
US-20250377596-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2025-12-11 US disclosed
US-20250362609-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING POLYFUNCTIONAL SULFONIC ACID NISSAN CHEMICAL CORPORATION (JP) 2025-11-27 US disclosed
US-20250355357-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2025-11-20 US disclosed
US-20250348001-A1 METHOD FOR PRODUCING LAMINATE AND METHOD FOR PRODUCING SEMICONDUCTOR ELEMENT NISSAN CHEMICAL CORPORATION (JP) 2025-11-13 US disclosed
US-20070173935-A1 Nucleus pulposus augmentation pretreatment technique DEPUY SPINE, INC. 2007-07-26 US disclosed
US-5096644-A Process for making a filled metathesis polymer article HERCULES INCORPORATED (US) 1992-03-17 US disclosed
EP-0349855-A2 Molded article of metathesis polymerized polymer containing fillers and process for its preparation HERCULES INCORPORATED (US) 1990-01-10 EP disclosed
US-4512926-A Process for the silylation of unsaturated, naturally occurring oils or the interesterification products thereof CHEMISCHE WERKE HUELS AG (DE) 1985-04-23 US disclosed
EP-0069216-B1 PROCESS FOR THE SILYLATION OF NATURAL UNSATURATED OILS, AND THEIR TRANSESTERIFICATION PRODUCTS HÜLS AKTIENGESELLSCHAFT (DE) 1985-03-27 EP disclosed
US-4396751-A Homo- and copolymers of 1,3-dienes containing reactive silyl groups, and their preparation and use CHEMISCHE WERKE HUELS AKTIENGESELLSCHAFT (DE) 1983-08-02 US disclosed
US-4381377-A Homo- or copolymers of 1,3-dienes carrying reactive silyl groups, their preparation and use CHEMISCHE WERKE HUELS, AG (DE) 1983-04-26 US disclosed
EP-0069216-A1 Process for the silylation of natural unsaturated oils, and their transesterification products HÜLS AKTIENGESELLSCHAFT (DE) 1983-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118764-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND SILICON-CONTAINING RESIST UNDERLAYER FILM SRSF1, MACF1, SRPK1 TSHR 4084/4885TDP1 2376/4885MEN1 2480/4885
US-12585188-B2 Composition for forming resist underlying film SRR, SMC1A, ASH2L TSHR 3614/4885TDP1 3751/4885MEN1 1625/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.