Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SCARB1 | Q8WTV0 | 2/20 | 0.39 |
| ▸ | PPM1D | O15297 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1173428 | 0.92 | ALDH1A1 (0.44) | ALDH1A1NPSR1KDM4ELMNACYP3A4 | |
| SCHEMBL5444222 | 0.83 | CDYL (0.41) | ALDH1A1NPSR1KDM4ELMNACYP3A4 | |
| SCHEMBL771509 | 0.83 | ALDH1A1 (0.44) | ALDH1A1NPSR1KDM4ELMNACYP3A4 | |
| SCHEMBL10293471 | 0.83 | ALDH1A1 (0.44) | ALDH1A1NPSR1KDM4ELMNACYP3A4 | |
| SCHEMBL3085979 | 0.81 | ALDH1A1 (0.40) | ALDH1A1NPSR1KDM4ELMNACYP3A4 | |
| SCHEMBL3094367 | 0.81 | RHEB (0.37) | ALDH1A1NPSR1KDM4ELMNACYP3A4 | |
| SCHEMBL1173483 | 0.81 | ALDH1A1 (0.42) | ALDH1A1NPSR1KDM4ELMNACYP3A4 | |
| SCHEMBL4821597 | 0.80 | ALDH1A1 (0.43) | ALDH1A1NPSR1KDM4ELMNACYP3A4 | |
| SCHEMBL391724 | 0.79 | ALDH1A1 (0.41) | ALDH1A1NPSR1KDM4ELMNACYP3A4 | |
| SCHEMBL13095926 | 0.79 | PRKCA (0.41) | PTGDR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | ISTITUTO DI RICERCHE DI BIOLOGIA DI MOLECULOARE P. ANGELETTI SPA (IT) | 2007-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167447-A1 | Indole acetamides as inhibitors of the hepatitis c virus ns5b polymerase | IDO1, NAT1, AANAT | ALDH1A1 119/4885NPSR1 458/4885KDM4E 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.