Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.50 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445709 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL7824959 | 0.80 | HPGD (0.63) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL5445850 | 0.79 | CNR1 (0.65) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL27686977 | 0.78 | ALDH1A1 (0.65) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL16229452 | 0.76 | SIRT2 (0.70) | SIRT2SIRT1 | |
| SCHEMBL7024489 | 0.74 | HDAC3 (0.66) | ALDH1A1HPGDNPC1RAB9ALMNA | |
| SCHEMBL30125025 | 0.74 | NPC1 (0.74) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL5455510 | 0.74 | NPC1 (0.74) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| SCHEMBL14096378 | 0.74 | ALDH1A1 (0.65) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL22871621 | 0.73 | HDAC3 (0.73) | ALDH1A1HPGDMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |