Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19113345 | 0.81 | — | — | |
| SCHEMBL20118159 | 0.77 | THRB (0.36) | THRBALOX15GAAMGAMSI | |
| SCHEMBL5597085 | 0.74 | CA1 (0.35) | CA1CA2HIF1ACTSD | |
| SCHEMBL11829302 | 0.74 | — | — | |
| SCHEMBL27807312 | 0.72 | ALOX15 (0.42) | THRBALOX15GAAMGAMSI | |
| SCHEMBL656778 | 0.71 | ALOX15 (0.42) | CA1CA2HIF1AALOX15GAA | |
| SCHEMBL559406 | 0.70 | ALOX15 (0.46) | CA1CA2THRBALOX15GAA | |
| SCHEMBL10542832 | 0.70 | S1PR2 (0.39) | CA1CA2ALDH1A1TSHR | |
| SCHEMBL15189342 | 0.70 | USP2 (0.52) | ALDH1A1MEN1KMT2AUSP2TSHR | |
| SCHEMBL29163507 | 0.70 | CTSD (0.43) | CA1CA2CTSDTHRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547717-B2 | Ion channel modulators | WYETH (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547717-B2 | Ion channel modulators | WYETH (US) | 2009-06-16 | — | — | US | disclosed |
| US-20080139560-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2008-06-12 | — | — | US | disclosed |
| US-20080139560-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2008-06-12 | — | — | US | disclosed |
| US-20070281937-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2007-12-06 | — | — | US | disclosed |
| US-20070281937-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2007-12-06 | — | — | US | disclosed |
| US-20070281937-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2007-12-06 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-20070208070-A1 | Ion channel modulators | WYETH | 2007-09-06 | — | — | US | disclosed |
| US-7235575-B2 | Guanidine mimics as factor Xa inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2007-06-26 | — | — | US | disclosed |
| CN-1934095-A | Ion channel modulators | WYETH CORP (US) | 2007-03-21 | — | — | CN | disclosed |
| EP-1723123-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2006-11-22 | — | — | EP | disclosed |
| EP-1723117-A2 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005087750-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2005-09-22 | — | — | WO | disclosed |
| WO-2005086836-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2005-09-22 | — | — | WO | disclosed |
| US-4622393-A | 3-vinyl-cephalosporins and their preparations | RHONE-POULENC INDUSTRIES (FR) | 1986-11-11 | — | — | US | disclosed |
| US-4415562-A | 3-Thiovinylcephalosporins and pharmaceutical compositions | RHONE-POULENC INDUSTRIES (FR) | 1983-11-15 | — | — | US | disclosed |
| US-3946032-A | Acetal derivatives of 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine-1-carboxaldehyde | CIBA-GEIGY CORPORATION (US) | 1976-03-23 | — | — | US | disclosed |
| US-3941799-A | 6-Substituted-11b-phenyl-3, 11bH-oxazirino[2,3-d]-s-triazol[4,3-a][1,4]benzodiazepines | CIBA-GEIGY CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208070-A1 | Ion channel modulators | CACNA1B, CACNA1C, TRPV1 | CA1 869/4885CA2 183/4885HIF1A 3067/4885 |
| US-20070281937-A1 | Ion Channel Modulators | CACNA1B, CACNA1C, TRPV1 | CA1 869/4885CA2 183/4885HIF1A 3067/4885 |
| US-20080139560-A1 | Ion Channel Modulators | CACNA1B, CACNA1C, TRPV1 | CA1 869/4885CA2 183/4885HIF1A 3067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.