Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5451832 | 0.84 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2GAAMAPTALOX12 | |
| SCHEMBL2344119 | 0.78 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2GAAMAPTALOX12 | |
| SCHEMBL5448199 | 0.78 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2GAAMAPTALOX12 | |
| SCHEMBL29661164 | 0.78 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2GAAMAPTALOX12 | |
| SCHEMBL5448122 | 0.77 | NPC1 (0.58) | ALDH1A1SMN1; SMN2GAAMAPTALOX12 | |
| SCHEMBL5456687 | 0.75 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2GAAMAPTALOX12 | |
| SCHEMBL31388347 | 0.73 | KMT2A (0.71) | ALDH1A1SMN1; SMN2GAAMAPTALOX12 | |
| SCHEMBL15777953 | 0.70 | AKT1 (0.62) | ALDH1A1SMN1; SMN2GAAMAPTALOX12 | |
| SCHEMBL11514088 | 0.70 | NOX1 (0.63) | ALDH1A1SMN1; SMN2GAAMAPTALOX12 | |
| SCHEMBL5453192 | 0.70 | EPHX1 (0.65) | ALDH1A1SMN1; SMN2MAPTALOX12NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |