Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.80 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.80 |
| ▸ | MAPT | P10636 | 5/20 | 0.80 |
| ▸ | GAA | P10253 | 2/20 | 0.80 |
| ▸ | RAB9A | P51151 | 6/20 | 0.74 |
| ▸ | NPC1 | O15118 | 5/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29661164 | 0.90 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2ALOX12MAPTGAA | |
| SCHEMBL2344119 | 0.90 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2ALOX12MAPTGAA | |
| SCHEMBL14096476 | 0.85 | RAB9A (1.00) | ALDH1A1SMN1; SMN2ALOX12MAPTGAA | |
| SCHEMBL12388857 | 0.84 | TAS1R3 (0.71) | ALDH1A1SMN1; SMN2ALOX12MAPTGAA | |
| SCHEMBL5452736 | 0.84 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2ALOX12MAPTGAA | |
| SCHEMBL9728573 | 0.83 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2ALOX12MAPTGAA | |
| SCHEMBL11514088 | 0.82 | NOX1 (0.63) | ALDH1A1SMN1; SMN2ALOX12MAPTGAA | |
| SCHEMBL5456687 | 0.81 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2ALOX12MAPTGAA | |
| SCHEMBL18550651 | 0.81 | EPHX1 (0.72) | ALDH1A1SMN1; SMN2ALOX12MAPTGAA | |
| SCHEMBL13454368 | 0.80 | MEN1 (0.60) | ALDH1A1SMN1; SMN2ALOX12MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |