Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13581610 | 0.85 | MAPT (0.71) | ALDH1A1MAPTALOX12SMN1; SMN2KDM4E | |
| SCHEMBL13453792 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MAPTALOX12SMN1; SMN2KDM4E | |
| SCHEMBL5448102 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MAPTALOX12SMN1; SMN2KDM4E | |
| SCHEMBL5451832 | 0.81 | ALDH1A1 (0.80) | ALDH1A1MAPTALOX12SMN1; SMN2KDM4E | |
| SCHEMBL5448122 | 0.80 | NPC1 (0.58) | ALDH1A1MAPTALOX12SMN1; SMN2KDM4E | |
| SCHEMBL5445708 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTALOX12SMN1; SMN2KDM4E | |
| SCHEMBL5447995 | 0.80 | MAPT (0.68) | ALDH1A1MAPTALOX12SMN1; SMN2KDM4E | |
| SCHEMBL9728405 | 0.79 | ALDH1A1 (0.77) | ALDH1A1MAPTALOX12SMN1; SMN2KDM4E | |
| SCHEMBL9818531 | 0.79 | ALDH1A1 (0.77) | ALDH1A1MAPTALOX12SMN1; SMN2KDM4E | |
| SCHEMBL5455495 | 0.78 | ALDH1A1 (0.72) | ALDH1A1MAPTALOX12SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |