SCHEMBL5452760

SCHEMBL5452760

COC(OC)C(C)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15770212 0.81 TSHR (0.37)
SCHEMBL1342663 0.73
SCHEMBL1343930 0.73
SCHEMBL21424233 0.73
SCHEMBL7641402 0.73 ALDH1A1 (0.33)
SCHEMBL8040302 0.71 LMNA (0.41)
SCHEMBL4741885 0.69
SCHEMBL6590316 0.69
SCHEMBL104305 0.69
SCHEMBL10340533 0.69 TSHR (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434940-B1 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID CO (US) 1996-05-29 EP claimed
US-5399716-A N-oxygenated arylpyrrole insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1995-03-21 US claimed
EP-0434940-A2 N-oxygenated arylpyrrole, insecticidal, acaricidal and nematicidal agents AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP claimed
EP-4712948-A2 GENE EDITING SYSTEMS AND COMPOSITIONS FOR TREATMENT OF HEMOGLOBINOPATHIES AND METHODS OF USING THE SAME Renagade Therapeutics Management Inc. (US) 2026-03-25 EP disclosed
WO-2024238828-A2 GENE EDITING SYSTEMS AND COMPOSITIONS FOR TREATMENT OF HEMOGLOBINOPATHIES AND METHODS OF USING THE SAME RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2024-11-21 WO disclosed
US-9079824-B2 Method for the synthesis of an amino acetal NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2015-07-14 US disclosed
EP-2885301-A1 AZAINDOLE CARBOXYLIC ACID AMIDES AND AZAINDOLE THIOCARBOXYLIC ACID AMIDES FOR USE AS INSECTICIDES AND ACARICIDES Bayer CropScience AG (DE) 2015-06-24 EP disclosed
WO-2014026984-A1 AZAINDOLE CARBOXYLIC ACID AMIDES AND AZAINDOLE THIOCARBOXYLIC ACID AMIDES FOR USE AS INSECTICIDES AND ACARICIDES BAYER CROPSCIENCE AG (DE) 2014-02-20 WO disclosed
US-20130165682-A1 METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2013-06-27 US disclosed
US-20070244241-A1 Resin Composition NISSHINBO INDUSTRIES, INC. (JP) 2007-10-18 US disclosed
EP-0885877-B1 Process for hydrogenation of cyanopropionaldehyde-containing cyanopropionaldehyde acetals AIR PROD & CHEM (US) 2000-04-12 EP disclosed
US-4864055-A ACETAL OF N-(OXOALKYL)ALKENAMIDE AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-09-05 US disclosed
US-4788288-A BINDERS; ADHESIVES; COATINGS FOR TEXTILE, PAPER AND CELLULOSE PRODUCTS; SOLVENT RESISTANCE AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-11-29 US disclosed
US-4691026-A Self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-09-01 US disclosed
US-4663410-A Polymers of self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-05-05 US disclosed
EP-0218827-A2 Polymers of self- and diol reactive formaldehyde-free crosslinking monomers AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-04-22 EP disclosed
EP-0215245-A1 Self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers and their derived polymers AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-03-25 EP disclosed
EP-0211432-A2 Polymers of self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and hemiamide ketal crosslinking monomers AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-02-25 EP disclosed
EP-0201693-A2 Self- and diol reactive formaldehyde-free crosslinking monomers and their derived polymers AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-11-20 EP disclosed
EP-0103126-A1 Process for preparing 4-amino-5-dialkoxymethylpyrimidine derivatives UBE INDUSTRIES, LTD. (JP) 1984-03-21 EP disclosed