Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452760 | 0.73 | — | — | |
| SCHEMBL15770212 | 0.69 | TSHR (0.37) | TSHR | |
| Water SCHEMBL8847349 | 0.69 | — | — | |
| SCHEMBL16993644 | 0.68 | — | — | |
| SCHEMBL9714737 | 0.67 | — | — | |
| SCHEMBL8888456 | 0.67 | — | — | |
| SCHEMBL15073460 | 0.65 | — | — | |
| SCHEMBL1023999 | 0.65 | — | — | |
| SCHEMBL3579282 | 0.65 | — | — | |
| SCHEMBL2813868 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395920-B1 | OBTAINING 2-SUBSTITUTED AND 2,2- DISUBSTITUTED ACETALS OF MALONDIALDEHYDE FROM ORTHO FORMATES AND SUBSTITUTED VINYL ETHERS IN THE PRESENCE OF AN ACIDIC CATALYST | CREANOVA, INC. | 2002-05-28 | — | — | US | disclosed |
| US-20020040166-A1 | PROCESS FOR PREPARING SUBSTITUTED ACETALS OF MALONDIALDEHYDE | CREANOVA, INC. | 2002-04-04 | — | — | US | disclosed |
| EP-0103126-B1 | PROCESS FOR PREPARING 4-AMINO-5-DIALKOXYMETHYLPYRIMIDINE DERIVATIVES | UBE INDUSTRIES, LTD. (JP) | 1987-03-04 | — | — | EP | disclosed |
| US-4492792-A | Process for preparing 4-amino-5-dialkoxy-methylpyrimidine derivatives | UBE INDUSTRIES, LTD. (JP) | 1985-01-08 | — | — | US | disclosed |
| EP-0103126-A1 | Process for preparing 4-amino-5-dialkoxymethylpyrimidine derivatives | UBE INDUSTRIES, LTD. (JP) | 1984-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040166-A1 | PROCESS FOR PREPARING SUBSTITUTED ACETALS OF MALONDIALDEHYDE | AOX1, GPX4, NOX4 | ALDH1A1 32/4885CYP3A4 210/4885ALOX15 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.