Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 19/20 | 0.67 |
| ▸ | ADRB3 | P13945 | 19/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445223 | 0.93 | ADRB2 (0.64) | ADRB2ADRB1ADRB3 | |
| SCHEMBL5448228 | 0.90 | ADRB2 (0.69) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6533461 | 0.90 | ADRB2 (0.69) | ADRB2ADRB1ADRB3 | |
| SCHEMBL927655 | 0.88 | ADRB2 (0.64) | ADRB2ADRB1ADRB3 | |
| SCHEMBL5443197 | 0.87 | ADRB2 (0.71) | ADRB2ADRB1ADRB3 | |
| SCHEMBL5456979 | 0.87 | ADRB2 (0.70) | ADRB2ADRB1ADRB3 | |
| Acetic Acid SCHEMBL5452874 | 0.87 | ADRB2 (0.78) | ADRB2ADRB1ADRB3 | |
| SCHEMBL5449493 | 0.86 | ADRB2 (0.77) | ADRB2ADRB1ADRB3 | |
| SCHEMBL5449483 | 0.86 | ADRB2 (0.77) | ADRB2ADRB1ADRB3 | |
| SCHEMBL5452170 | 0.85 | ADRB2 (0.64) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249630-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LIMITED (GB) | 2007-10-25 | — | — | US | disclosed |
| US-20050209338-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | GLAXO GROUP LIMITED (GB) | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209338-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | PHOSPHO1, PNMT, PEBP1 | ADRB2 89/4885ADRB1 192/4885ADRB3 128/4885 |
| US-20070249630-A1 | Phenethanolamine derivatives for treatment of respiratory diseases | PHOSPHO1, PNMT, PEBP1 | ADRB2 89/4885ADRB1 192/4885ADRB3 128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.