Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.58 |
| ▸ | DRD2 | P14416 | 8/20 | 0.58 |
| ▸ | DRD3 | P35462 | 8/20 | 0.58 |
| ▸ | HTR6 | P50406 | 8/20 | 0.58 |
| ▸ | HTR2A | P28223 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14580859 | 1.00 | HTR2C (0.58) | HTR2CDRD2DRD3HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL5438399 | 0.99 | HTR2C (0.57) | HTR2CDRD2DRD3HTR6HTR2A | |
| SCHEMBL14580861 | 0.88 | HTR2C (0.55) | HTR2CDRD2DRD3HTR6HTR2A | |
| SCHEMBL14580866 | 0.88 | DRD2 (0.44) | HTR2CDRD2DRD3HTR6HTR2A | |
| SCHEMBL14580867 | 0.88 | DRD2 (0.44) | HTR2CDRD2DRD3HTR6HTR2A | |
| SCHEMBL5443058 | 0.85 | DRD2 (0.49) | HTR2CDRD2DRD3HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL5443529 | 0.85 | DRD2 (0.48) | HTR2CDRD2DRD3HTR6HTR2A | |
| SCHEMBL5445098 | 0.83 | DRD2 (0.60) | HTR2CDRD2DRD3HTR6HTR2A | |
| SCHEMBL5435607 | 0.83 | DRD2 (0.60) | HTR2CDRD2DRD3HTR6HTR2A | |
| Hydrochloric Acid SCHEMBL5443066 | 0.82 | DRD2 (0.59) | HTR2CDRD2DRD3HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043026-A1 | Dopamine receptor modulators as antipsychotic agents | GLAXO GROUP LIMITED (GB) | 2007-02-22 | — | — | US | claimed |
| US-20070043026-A1 | Dopamine receptor modulators as antipsychotic agents | GLAXO GROUP LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
| US-20070043026-A1 | Dopamine receptor modulators as antipsychotic agents | GLAXO GROUP LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043026-A1 | Dopamine receptor modulators as antipsychotic agents | SIGMAR1, CHRM1, OPRM1 | HTR2C 30/4885DRD2 25/4885DRD3 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.