Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.54 |
| ▸ | CDK9 | P50750 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 8/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.53 |
| ▸ | CLK1 | P49759 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KCNN3 | Q9UGI6 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456522 | 0.90 | CDK2 (0.63) | TP53CCNT1CDK9CDK2CCNE1 | |
| SCHEMBL31560186 | 0.90 | CDK2 (0.66) | TP53CCNT1CDK9CDK2CCNE1 | |
| SCHEMBL31560200 | 0.86 | CDK2 (0.61) | TP53CDK2CCNE1KDM4EALDH1A1 | |
| SCHEMBL5454018 | 0.86 | CDK2 (0.67) | TP53CDK2CCNE1KCNN3 | |
| SCHEMBL5463452 | 0.86 | CDK2 (0.61) | TP53CCNT1CDK9CDK2CCNE1 | |
| SCHEMBL5463491 | 0.85 | CDK2 (0.49) | TP53CCNT1CDK9CDK2CCNE1 | |
| SCHEMBL5448078 | 0.85 | CDK2 (0.51) | TP53CCNT1CDK9CDK2CCNE1 | |
| SCHEMBL5449818 | 0.84 | CDK2 (0.48) | TP53CCNT1CDK9CDK2CCNE1 | |
| SCHEMBL5468155 | 0.83 | KCNN3 (0.55) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL31560174 | 0.82 | ALDH1A1 (0.55) | TP53CCNT1CDK9CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-15 | — | — | US | claimed |
| EP-1671962-A1 | NOVEL FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-21 | — | — | EP | claimed |
| CN-119899187-A | Synthesis method of pyrazolo [1,5-a ] pyrimidine-7-amine compound | 湖南九典制药股份有限公司 | 2025-04-29 | — | — | CN | disclosed |
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| EP-1671962-A1 | NOVEL FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | JUN, CHUK, RELA | TP53 840/4885CCNT1 105/4885CDK9 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.