Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.81 |
| ▸ | RAB9A | P51151 | 6/20 | 0.81 |
| ▸ | GAA | P10253 | 5/20 | 0.81 |
| ▸ | NPC1 | O15118 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | CCR6 | P51684 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11921406 | 0.88 | ALDH1A1 (0.74) | ALDH1A1RAB9AGAANPC1MAPT | |
| SCHEMBL5448004 | 0.86 | ALDH1A1 (0.72) | ALDH1A1RAB9AGAANPC1MAPT | |
| SCHEMBL9901505 | 0.85 | CYP2C19 (0.72) | ALDH1A1RAB9AGAANPC1MAPT | |
| SCHEMBL5442280 | 0.81 | CA1 (0.76) | ALDH1A1RAB9AGAANPC1MAPT | |
| SCHEMBL3044660 | 0.81 | EPHX1 (0.69) | ALDH1A1MAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27232945 | 0.81 | RAB9A (0.76) | ALDH1A1RAB9AGAANPC1MAPT | |
| SCHEMBL5447995 | 0.80 | MAPT (0.68) | ALDH1A1RAB9AGAANPC1MAPT | |
| SCHEMBL14096348 | 0.80 | NPC1 (0.55) | ALDH1A1RAB9AGAANPC1MAPT | |
| SCHEMBL5450582 | 0.80 | ALDH1A1 (0.66) | ALDH1A1RAB9AGAANPC1MAPT | |
| SCHEMBL14096510 | 0.80 | ALDH1A1 (1.00) | ALDH1A1RAB9AGAANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |