Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | HTT | P42858 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | CCR6 | P51684 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12225787 | 0.86 | KCNMA1 (0.72) | MAPTKDM4EHTTNPSR1TDP1 | |
| SCHEMBL11512341 | 0.81 | EPHX1 (0.80) | KDM4EHTTNPSR1ALDH1A1KMT2A | |
| SCHEMBL5452992 | 0.80 | ALDH1A1 (0.81) | MAPTKDM4EHTTNPSR1TDP1 | |
| SCHEMBL5456687 | 0.80 | ALDH1A1 (0.67) | MAPTKDM4EHTTNPSR1TDP1 | |
| SCHEMBL10144149 | 0.79 | ALDH1A1 (0.69) | MAPTKDM4EHTTTDP1ALDH1A1 | |
| SCHEMBL15966210 | 0.79 | MAPT (0.67) | MAPTKDM4EHTTNPSR1TDP1 | |
| SCHEMBL5445708 | 0.77 | ALDH1A1 (0.62) | MAPTKDM4EHTTTDP1ALDH1A1 | |
| SCHEMBL11513179 | 0.76 | EPHX1 (0.71) | MAPTNPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL8658939 | 0.76 | ALDH1A1 (0.62) | MAPTKDM4EHTTNPSR1TDP1 | |
| SCHEMBL9818531 | 0.76 | ALDH1A1 (0.77) | MAPTKDM4EHTTNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |