SCHEMBL5453225

SCHEMBL5453225

FN(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9903892 0.97 LMNA (0.40) LMNA
SCHEMBL345872 0.97 LMNA (0.40) LMNA
SCHEMBL9636964 0.94 LMNA (0.32) LMNA
SCHEMBL3657606 0.94 LMNA (0.38) LMNA
SCHEMBL9903342 0.94 LMNA (0.38) LMNA
SCHEMBL9686592 0.94 LMNA (0.38) LMNA
SCHEMBL7949744 0.91 LMNA (0.36) LMNA
SCHEMBL17092890 0.91 LMNA (0.36) LMNA
Hydrochloric Acid SCHEMBL3297398 0.91 LMNA (0.36) LMNA
SCHEMBL28581071 0.91 LMNA (0.36) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1860141-B1 Process for the surface modification of a polymer substrate and polymers formed therefrom AMO UPPSALA AB (SE) 2013-12-25 EP disclosed
EP-1860141-A1 Process for the surface modification of a polymer substrate and polymers formed therefrom Advanced Medical Optics Uppsala AB (SE) 2007-11-28 EP disclosed
US-20070066779-A1 Fluorine-containing photocurable composition DIC CORPORATION (JP) 2007-03-22 US disclosed
US-6943204-B2 Process for the modification of elastomers with surface interpenetrating polymer networks and elastomers formed therefrom ADVANCED MEDICAL OPTICS UPPSALA AB (SE) 2005-09-13 US disclosed
EP-0889067-B1 Amorphous hexafluoropropylene (HFP) / tetrafluoroethylene (TFE) copolymers DU PONT (US) 2004-07-28 EP disclosed
EP-0889066-B1 Amorphous copolymers containing hexafluoropropylene DU PONT (US) 2004-06-09 EP disclosed
EP-0808335-B1 AMORPHOUS TETRAFLUOROETHYLENE-HEXAFLUOROPROPYLENE COPOLYMERS DU PONT (US) 2002-12-11 EP disclosed
US-6486280-B1 Amorphous tetrafluoroethylene-hexafluoropropylene copolymers E. I. DU PONT DE NEMOURS AND COMPANY 2002-11-26 US disclosed
US-6251965-B1 SILICONE INTRAOCULAR LENSES PHARMACIA AB (SE) 2001-06-26 US disclosed
US-6133389-A COATING, ENCAPSULANT COMPRISING FLUOROPOLYMER BLEND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-10-17 US disclosed
EP-0891994-A1 Initiator for making amorphous tetrafluoroethylene-hexafluoropropylene copolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-20 EP disclosed
EP-0889028-A2 Initiator for the copolymerization of tetrafluoroethylene and hexafluoropropylene E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-07 EP disclosed
EP-0889067-A1 Amorphous HFP/TFE copolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-07 EP disclosed
EP-0889066-A1 Amorphous copolymers containing tetrafluoroethylene and hexafluoropropylene E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-01-07 EP disclosed
EP-0808335-A2 AMORPHOUS TETRAFLUOROETHYLENE-HEXAFLUOROPROPYLENE COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-11-26 EP disclosed
US-5663255-A POLYMERS FOR COATINGS, FILMS AND ENCAPSULATION WITH LOW COST POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-02 US disclosed
US-5637663-A RADICAL INITIATING A CONTINUOUS COPOLYMERIZATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-06-10 US disclosed
WO-1996024624-A2 AMORPHOUS TETRAFLUOROETHYLENE-HEXAFLUOROPROPYLENE COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-15 WO disclosed
US-5478905-A Reacting tetrafluoroethylene and hexafluoropropylene in the presence of a radical initiator E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-12-26 US disclosed