SCHEMBL9686592

SCHEMBL9686592

FN(C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3657606 1.00 LMNA (0.38) LMNATHRB
SCHEMBL9903342 1.00 LMNA (0.38) LMNATHRB
Hydrochloric Acid SCHEMBL3297398 0.97 LMNA (0.36) LMNATHRB
SCHEMBL345872 0.97 LMNA (0.40) LMNATHRB
SCHEMBL9903892 0.97 LMNA (0.40) LMNATHRB
SCHEMBL5453225 0.94 LMNA (0.35) LMNA
SCHEMBL7949744 0.91 LMNA (0.36) LMNATHRB
SCHEMBL17092890 0.91 LMNA (0.36) LMNATHRB
SCHEMBL28581071 0.91 LMNA (0.36) LMNATHRB
SCHEMBL29204671 0.90 LMNA (0.30) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5079155-A Bioaffinity chromatography E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-01-07 US disclosed