SCHEMBL5453313

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5445123	0.88	KMT2A (0.34)	TSHRKMT2AHPGDMAPTHTT
	SCHEMBL5455615	0.88	KMT2A (0.33)	TSHRKMT2AHPGDMAPTHTT
	SCHEMBL5446947	0.85	TSHR (0.33)	TSHRKMT2AHPGDMAPTHTT
	SCHEMBL5443989	0.82	ADORA3 (0.39)	TSHRKMT2AHPGDMAPTHTT
	SCHEMBL5453316	0.82	HPGD (0.32)	TSHRKMT2AHPGDMAPTHTT
	SCHEMBL5440174	0.82	KMT2A (0.34)	TSHRKMT2AHPGDMAPTHTT
	SCHEMBL5451001	0.80	L3MBTL1 (0.37)	TSHRKMT2AHPGDMAPTHTT
	SCHEMBL5444083	0.79	GRM5 (0.34)	KMT2AHPGDMAPTHTTRAB9A
	SCHEMBL5441173	0.79	ADORA3 (0.40)	TSHRKMT2AHPGDMAPTHTT
	SCHEMBL5446920	0.77	L3MBTL1 (0.39)	TSHRKMT2AHPGDMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.