Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151703 | 0.85 | LMNA (0.53) | MAPK1LMNAATMKDM4EALDH1A1 | |
| SCHEMBL2688919 | 0.79 | LIMK1 (0.62) | MAPK1LMNALIMK1IKBKBATM | |
| SCHEMBL31350344 | 0.77 | LIMK1 (0.56) | MAPK1LMNALIMK1IKBKBATM | |
| SCHEMBL5453335 | 0.77 | LIMK1 (0.60) | MAPK1LMNALIMK1IKBKBATM | |
| Hydrochloric Acid SCHEMBL7300365 | 0.76 | LIMK1 (0.54) | MAPK1LMNALIMK1IKBKBATM | |
| SCHEMBL10624355 | 0.75 | LIMK1 (0.58) | MAPK1LMNALIMK1IKBKBATM | |
| SCHEMBL6656348 | 0.73 | LMNA (0.69) | MAPK1LMNAATMKDM4EALDH1A1 | |
| SCHEMBL9495325 | 0.71 | LMNA (1.00) | MAPK1LMNALIMK1ATMKDM4E | |
| SCHEMBL11756032 | 0.71 | LIMK1 (0.57) | MAPK1LMNALIMK1IKBKBATM | |
| SCHEMBL9272529 | 0.71 | PTPN2 (0.43) | MAPK1LMNAATMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382770-B | A method of alpha-amido oximido ether compound is synthesized by N- alkoxy amide and 2H- aziridine | 浙江大学 | 2019-07-09 | — | — | CN | disclosed |
| CN-107382770-A | A kind of method that α amino oximido ether compounds are synthesized by N alkoxy amides and 2H aziridine | 浙江大学 | 2017-11-24 | — | — | CN | disclosed |
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | GPC BIOTECH AG (DE) | 2007-11-29 | — | — | US | disclosed |
| EP-1670804-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC Biotech AG (DE) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005023818-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC BIOTECH AG (DE) | 2005-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070275962-A1 | Heterobicyclic Compounds as Pharmaceutically Active Agents | TBCA, PARK7, NFATC1 | MAPK1 1176/4885LMNA 3232/4885LIMK1 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.