Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | RAF1 | P04049 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336669 | 0.82 | MAPT (0.54) | MAPTSMN1; SMN2MAPK1RAF1HTT | |
| SCHEMBL5467182 | 0.80 | MAPT (0.56) | MAPTSMN1; SMN2MAPK1RAF1HTT | |
| SCHEMBL5334693 | 0.78 | TP53 (0.68) | MAPTMAPK1HTTHPGDALDH1A1 | |
| SCHEMBL3799566 | 0.77 | MAPT (0.61) | MAPTSMN1; SMN2MAPK1RAF1HTT | |
| SCHEMBL13164963 | 0.77 | MAPK1 (1.00) | MAPTSMN1; SMN2MAPK1RAF1HTT | |
| SCHEMBL5467523 | 0.77 | RAB9A (0.76) | MAPTMAPK1HTTHPGDNPSR1 | |
| SCHEMBL3804302 | 0.76 | MAPT (0.64) | MAPTSMN1; SMN2MAPK1RAF1HTT | |
| SCHEMBL3803118 | 0.75 | MKNK2 (0.60) | MKNK1MKNK2 | |
| SCHEMBL13165061 | 0.73 | SMN1; SMN2 (0.64) | MAPTSMN1; SMN2MAPK1RAF1HTT | |
| SCHEMBL15426163 | 0.73 | FGFR1 (0.67) | LMNACSNK2A2CSNK2BCSNK2A1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099877-A1 | N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CYTOVIA, INC. (US) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099877-A1 | N-aryl-thienopyrimidin-4-amines and analogs as activators of caspases and inducers of apoptosis and the use thereof | CASP4, CASP3, API5 | MAPT 4267/4885SMN1; SMN2 3131/4885MAPK1 2419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.