Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458329 | 0.84 | LMNA (0.44) | LMNANPC1RAB9AHTTALDH1A1 | |
| SCHEMBL5461144 | 0.81 | MEN1 (0.54) | LMNAPKMNPC1RAB9AALDH1A1 | |
| SCHEMBL23132428 | 0.77 | HCAR2 (0.49) | NPC1RAB9AHTTRARARXRA | |
| SCHEMBL19459379 | 0.74 | TYR (0.41) | NPC1RAB9AHTTRARARXRA | |
| SCHEMBL744240 | 0.73 | NOTUM (0.48) | HTTALDH1A1FDPSHCAR2SMN1; SMN2 | |
| SCHEMBL5458534 | 0.72 | MEN1 (0.60) | LMNANPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL5449783 | 0.72 | DAO (0.48) | LMNANPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL5445324 | 0.71 | ALDH1A1 (0.55) | LMNANPC1RAB9AHTTALDH1A1 | |
| SCHEMBL2131964 | 0.71 | TP53 (0.50) | NPC1RAB9AHTTALDH1A1FDPS | |
| SCHEMBL5447826 | 0.70 | SMN1; SMN2 (0.43) | LMNANPC1RAB9AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043062-A1 | Isoxazoles as peptide deformylase inhibitors | ARPIDA A/S (DK) | 2007-02-22 | — | — | US | claimed |
| EP-1664000-A1 | ISOXAZOLES AS PEPTIDE DEFORMYLASE INHIBITORS | Arpida A/S (DK) | 2006-06-07 | — | — | EP | claimed |
| WO-2005026133-A1 | ISOXAZOLES AS PEPTIDE DEFORMYLASE INHIBITORS | ARPIDA A/S (DK) | 2005-03-24 | — | — | WO | claimed |
| US-20070043062-A1 | Isoxazoles as peptide deformylase inhibitors | ARPIDA A/S (DK) | 2007-02-22 | — | — | US | disclosed |
| US-20070043062-A1 | Isoxazoles as peptide deformylase inhibitors | ARPIDA A/S (DK) | 2007-02-22 | — | — | US | disclosed |
| US-20070043062-A1 | Isoxazoles as peptide deformylase inhibitors | ARPIDA A/S (DK) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043062-A1 | Isoxazoles as peptide deformylase inhibitors | PDF, MRPL21, PEPD | LMNA 2510/4885PKM 927/4885NPC1 1545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.