Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 4/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HRH2 | P25021 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446820 | 0.94 | SMN1; SMN2 (0.61) | KMT2ASMN1; SMN2DRD2CNR1NR2F2 | |
| SCHEMBL14411257 | 0.94 | SMN1; SMN2 (0.61) | KMT2ASMN1; SMN2DRD2CNR1NR2F2 | |
| SCHEMBL14411340 | 0.86 | KAT2B (0.54) | KMT2ASMN1; SMN2DRD2NR2F2ALDH1A1 | |
| SCHEMBL5454286 | 0.86 | MAPT (0.59) | KMT2ASMN1; SMN2DRD2CNR1ALDH1A1 | |
| SCHEMBL5453370 | 0.84 | KMT2A (0.58) | KMT2ASMN1; SMN2DRD2CNR1ALDH1A1 | |
| SCHEMBL5460381 | 0.84 | HRH2 (0.57) | KMT2ASMN1; SMN2DRD2HRH2CNR2 | |
| SCHEMBL5444486 | 0.84 | HTR2A (0.52) | KMT2ASMN1; SMN2DRD2CNR1ALDH1A1 | |
| SCHEMBL5454214 | 0.83 | DRD2 (0.52) | KMT2ASMN1; SMN2DRD2ALDH1A1MAPT | |
| SCHEMBL14410967 | 0.83 | DRD2 (0.52) | KMT2ASMN1; SMN2DRD2CNR1HRH2 | |
| SCHEMBL5440970 | 0.83 | HRH2 (0.51) | KMT2ASMN1; SMN2DRD2CNR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-09-13 | — | — | US | disclosed |
| WO-2007079239-A2 | BICYCLIC NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | ACADIA PHARMACEUTICALS INC. (US) | 2007-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213359-A1 | BICYCLIC-NITROGEN COMPOUNDS AS MODULATORS OF GHRELIN RECEPTOR AND USES THEREOF | GIPR, GHSR, GHRHR | KMT2A 4056/4885SMN1; SMN2 1701/4885DRD2 2688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.