Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.63 |
| ▸ | BCR | P11274 | 5/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.57 |
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.48 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL324161 | 0.89 | PARP10 (0.59) | ABL1BCREPHX2FAAHTRPV1 | |
| Hydrochloric Acid SCHEMBL11888844 | 0.88 | PARP10 (0.57) | ABL1BCREPHX2FAAHTRPV1 | |
| Hydrochloric Acid SCHEMBL3785321 | 0.88 | PARP10 (0.57) | ABL1BCREPHX2FAAHTRPV1 | |
| SCHEMBL22721370 | 0.86 | TRPV1 (0.76) | ABL1EPHX2FAAHTRPV1MAPT | |
| SCHEMBL5473190 | 0.85 | EPHX2 (0.70) | ABL1BCREPHX2FAAHTRPV1 | |
| SCHEMBL22740915 | 0.84 | PARP10 (0.53) | ABL1BCREPHX2FAAHTRPV1 | |
| SCHEMBL8297933 | 0.84 | ABL1 (0.56) | ABL1BCREPHX2FAAHTRPV1 | |
| SCHEMBL22721342 | 0.84 | PARP10 (0.70) | ABL1BCREPHX2FAAHTRPV1 | |
| SCHEMBL20805842 | 0.83 | EPHX2 (0.77) | ABL1BCREPHX2FAAHTRPV1 | |
| SCHEMBL3194551 | 0.82 | MAPT (0.61) | ABL1BCREPHX2TRPV1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129433-A1 | Diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2007-06-07 | — | — | US | claimed |
| EP-1687253-A2 | DIPHENYLAMINE DERIVATIVES | Merk Patent Gmbh (DE) | 2006-08-09 | — | — | EP | claimed |
| WO-2005051888-A2 | DIPHENYLAMINE DERIVATIVES | MERK PATENT GMBH (DE) | 2005-06-09 | — | — | WO | claimed |
| US-20070129433-A1 | Diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
| US-20070129433-A1 | Diphenylamine derivatives | MERCK PATENT GMBH (DE) | 2007-06-07 | — | — | US | disclosed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070072915-A1 | Novel phenoxyacetamide derivative and use thereof for preparation of diphenylamines | MERCK PATENT GMBH (DE) | 2007-03-29 | — | — | US | disclosed |
| US-20070072915-A1 | Novel phenoxyacetamide derivative and use thereof for preparation of diphenylamines | MERCK PATENT GMBH (DE) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072915-A1 | Novel phenoxyacetamide derivative and use thereof for preparation of diphenylamines | PNMT, AADAC, INMT | ABL1 200/4885BCR 3830/4885EPHX2 658/4885 |
| US-20070123586-A1 | Nitroso derivatives of diphenylamine | NOS3, CBR3, CBR1 | ABL1 576/4885BCR 1132/4885EPHX2 2041/4885 |
| US-20070129433-A1 | Diphenylamine derivatives | CCNY, CHKB, CHKA | ABL1 136/4885BCR 2468/4885EPHX2 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.