Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.65 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.65 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
| ▸ | RHEB | Q15382 | 1/20 | 0.57 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.57 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.52 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23132141 | 0.88 | PKN1 (0.61) | ALDH1A1KDM4EPKMHPGDNPC1 | |
| Hydrochloric Acid SCHEMBL7271236 | 0.87 | PKN1 (0.59) | ALDH1A1KDM4EPKMHPGDNPC1 | |
| SCHEMBL30104576 | 0.80 | ALDH1A1 (0.71) | ALDH1A1KDM4EPKMHPGDNPC1 | |
| SCHEMBL21565901 | 0.80 | ALDH1A1 (0.71) | ALDH1A1KDM4EPKMHPGDNPC1 | |
| SCHEMBL7437914 | 0.80 | ALDH1A1 (0.71) | ALDH1A1KDM4EPKMHPGDNPC1 | |
| SCHEMBL3337258 | 0.80 | NPC1 (0.66) | ALDH1A1KDM4EPKMHPGDNPC1 | |
| SCHEMBL16331618 | 0.80 | ALDH1A1 (0.71) | ALDH1A1KDM4EPKMHPGDNPC1 | |
| SCHEMBL6245632 | 0.80 | ALDH1A1 (0.71) | ALDH1A1KDM4EPKMHPGDNPC1 | |
| SCHEMBL9694046 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EPKMHPGDNPC1 | |
| SCHEMBL16332640 | 0.80 | ALDH1A1 (1.00) | ALDH1A1KDM4EPKMHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12577242-B2 | Pyrrolopyridine and imidazopyridine antiviral compounds | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2026-03-17 | — | — | US | disclosed |
| US-20230130598-A1 | PYRROLOPYRIDINE AND IMIDAZOPYRIDINE ANTIVIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-04-27 | — | — | US | disclosed |
| US-20230130598-A1 | PYRROLOPYRIDINE AND IMIDAZOPYRIDINE ANTIVIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-04-27 | — | — | US | disclosed |
| US-20230130598-A1 | PYRROLOPYRIDINE AND IMIDAZOPYRIDINE ANTIVIRAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2023-04-27 | — | — | US | disclosed |
| EP-4110777-A1 | PYRROLOPYRIDINE AND IMIDAZOPYRIDINE ANTIVIRAL COMPOUNDS | Katholieke Universiteit Leuven, K.U.Leuven R&D (BE) | 2023-01-04 | — | — | EP | disclosed |
| CN-115175909-A | Pyrrolopyridine and imidazopyridine antiviral compounds | 鲁汶天主教大学 | 2022-10-11 | — | — | CN | disclosed |
| US-20070191420-A1 | Kinase inhibitors | DEVGEN NV | 2007-08-16 | — | — | US | disclosed |
| EP-1715862-A1 | KINASE INHIBITORS | Devgen NV (BE) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005082367-A1 | KINASE INHIBITORS | DEVGEN NV (BE) | 2005-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230130598-A1 | PYRROLOPYRIDINE AND IMIDAZOPYRIDINE ANTIVIRAL COMPOUNDS | SARS1, TPI1, TPMT | ALDH1A1 1430/4885KDM4E 3519/4885PKM 124/4885 |
| US-12577242-B2 | Pyrrolopyridine and imidazopyridine antiviral compounds | SARS1, TPMT, ZC3HAV1 | ALDH1A1 3438/4885KDM4E 612/4885PKM 2288/4885 |
| US-20070191420-A1 | Kinase inhibitors | ROCK1, ROCK2, MAP3K20 | ALDH1A1 4377/4885KDM4E 569/4885PKM 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.