Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460965 | 0.85 | ADORA1 (0.53) | FYNADORA2BCDK2CCNT1CCNA2 | |
| Ammonia Solution, Strong SCHEMBL5454694 | 0.84 | ADORA1 (0.52) | FYNADORA2BCDK2CCNT1CCNA2 | |
| SCHEMBL4053436 | 0.80 | ADORA2B (0.60) | FYNADORA2BCDK2MTORADORA1 | |
| SCHEMBL5452581 | 0.78 | ADORA1 (0.48) | FYNADORA2BCDK2ADORA1ADORA2A | |
| SCHEMBL4059869 | 0.78 | PIK3R1 (0.43) | FYNADORA2BMTORADORA1ADORA2A | |
| SCHEMBL5459579 | 0.76 | ADORA1 (0.55) | FYNADORA2BCDK2CCNT1CCNA2 | |
| SCHEMBL5453900 | 0.75 | ADORA1 (0.42) | ADORA2BADORA1ADORA2AADORA3MAPK14 | |
| SCHEMBL5451373 | 0.74 | ADORA1 (0.53) | FYNADORA2BADORA1ADORA2AADORA3 | |
| SCHEMBL4052377 | 0.74 | MTOR (0.43) | FYNADORA2BMTORADORA1ADORA2A | |
| SCHEMBL5450282 | 0.74 | WNT3A (0.45) | ADORA2BADORA1ADORA2AADORA3MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054876-A1 | Pharmaceutical composition promoting defecation | YASUDA MASAHIRO | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054876-A1 | Pharmaceutical composition promoting defecation | ADORA2B, ADORA2A, ADORA1 | FYN 4325/4885ADORA2B 1/4885CDK2 2634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.