SCHEMBL5454961

SCHEMBL5454961

S=C(Nc1ccccc1)Nc1cccc(Cl)c1

nearest known ligand 0.89

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.75
MEN1 O00255 2/20 0.75
KMT2A Q03164 2/20 0.75
ALDH1A1 P00352 1/20 0.75
MAOA P21397 1/20 0.75
IDO1 P14902 1/20 0.71
LMNA P02545 2/20 0.69
PLA2G1B P04054 1/20 0.69
HPGD P15428 1/20 0.69
ATG4B Q9Y4P1 1/20 0.69
NPC1 O15118 1/20 0.68
MAPT P10636 1/20 0.68
HTT P42858 1/20 0.68
RAB9A P51151 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26991 0.94 IDO1 (0.79) MAOBMEN1KMT2AALDH1A1MAOA
SCHEMBL29481122 0.94 IDO1 (0.79) MAOBMEN1KMT2AALDH1A1MAOA
SCHEMBL11067896 0.91 ALDH1A1 (0.78) MAOBMEN1KMT2AALDH1A1MAOA
SCHEMBL22274845 0.86 IDO1 (0.73) MAOBMEN1KMT2AALDH1A1MAOA
SCHEMBL16566455 0.86 MAOB (1.00) MAOBMEN1KMT2AALDH1A1MAOA
SCHEMBL6811430 0.86 MEN1 (0.71) MAOBMEN1KMT2AALDH1A1MAOA
SCHEMBL16566457 0.86 MEN1 (0.71) MAOBMEN1KMT2AALDH1A1MAOA
SCHEMBL16566486 0.84 ALDH1A1 (0.69) MEN1KMT2AALDH1A1IDO1NPC1
SCHEMBL11260245 0.84 IDO1 (0.65) MAOBMEN1KMT2AALDH1A1MAOA
SCHEMBL16566480 0.84 MEN1 (0.80) MAOBMEN1KMT2AALDH1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4421344-A THIOUREA, AND ZINC OXIDE OR HYDROXIDE TO PREVENT FADING OJI PAPER CO., LTD. (JP) 1983-12-20 US claimed
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
CN-101129295-A 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2008-02-27 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed
US-4421344-A THIOUREA, AND ZINC OXIDE OR HYDROXIDE TO PREVENT FADING OJI PAPER CO., LTD. (JP) 1983-12-20 US disclosed
US-4035244-A Electric recording process MITA INDUSTRIAL COMPANY LIMITED (JA) 1977-07-12 US disclosed