Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | MAOA | P21397 | 1/20 | 0.78 |
| ▸ | MAOB | P27338 | 1/20 | 0.78 |
| ▸ | IDO1 | P14902 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26991 | 0.92 | IDO1 (0.79) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL29481122 | 0.92 | IDO1 (0.79) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL5454961 | 0.91 | MAOB (0.75) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL16566455 | 0.88 | MAOB (1.00) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL16566457 | 0.88 | MEN1 (0.71) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL6811430 | 0.88 | MEN1 (0.71) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL16566494 | 0.86 | ALDH1A1 (0.71) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL6815121 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL22274845 | 0.85 | IDO1 (0.73) | ALDH1A1MEN1KMT2AMAOAMAOB | |
| SCHEMBL16566470 | 0.84 | MEN1 (0.77) | ALDH1A1MEN1KMT2AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | RAHMAN ATTA-UR (PK) | 2015-03-19 | — | — | US | disclosed |
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | RAHMAN ATTA-UR (PK) | 2015-03-19 | — | — | US | disclosed |
| US-4461821-A | Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound | FUJI PHOTO FILM CO., LTD. (JP) | 1984-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | SERPINB1, CTRL, RNASE1 | ALDH1A1 1629/4885MEN1 4431/4885KMT2A 2472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.