Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 3/20 | 0.45 |
| ▸ | FNTB | P49356 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30218692 | 0.86 | TRPV1 (0.52) | TRPV1MAPTPGRHTR1AADORA3 | |
| SCHEMBL15246439 | 0.86 | TRPV1 (0.52) | TRPV1MAPTPGRHTR1AADORA3 | |
| SCHEMBL14815644 | 0.86 | TRPV1 (0.52) | TRPV1MAPTPGRHTR1AADORA3 | |
| SCHEMBL21436889 | 0.85 | TRPV1 (0.53) | TRPV1MAPTPGRHTR1AADORA3 | |
| Squalene SCHEMBL23198699 | 0.79 | KMT2A (0.55) | TRPV1MAPTPGRHTR1AADORA3 | |
| SCHEMBL7930022 | 0.76 | MAPT (0.49) | TRPV1MAPTPGRHTR1AADORA3 | |
| SCHEMBL6463435 | 0.76 | MAPT (0.49) | TRPV1MAPTPGRHTR1AADORA3 | |
| SCHEMBL2289564 | 0.76 | MAPT (0.49) | TRPV1MAPTPGRHTR1AADORA3 | |
| SCHEMBL2236562 | 0.76 | MAPT (0.49) | TRPV1MAPTPGRHTR1AADORA3 | |
| SCHEMBL6028170 | 0.76 | MAPT (0.49) | TRPV1MAPTPGRHTR1AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637578-B2 | Reagents and methods for the formation of disulfide bonds and the glycosylation of proteins | ISIS INNOVATION LIMITED (GB) | 2014-01-28 | — | — | US | disclosed |
| US-20070213506-A1 | Reagents And Methods For The Formation Of Disulfide Bonds And The Glycosylation Of Proteins | ISIS INNOVATION LIMITED (GB) | 2007-09-13 | — | — | US | disclosed |
| EP-1644390-A2 | REAGENTS AND METHODS FOR THE FORMATION OF DISULFIDE BONDS AND THE GLYCOSYLATION OF PROTEINS | ISIS INNOVATION LIMITED (GB) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005000862-A2 | REAGENTS AND METHODS FOR THE FORMATION OF DISULFIDE BONDS AND THE GLYCOSYLATION OF PROTEINS | ISIS INNOVATION LIMITED (GB) | 2005-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213506-A1 | Reagents And Methods For The Formation Of Disulfide Bonds And The Glycosylation Of Proteins | SCLY, PTMS, TST | TRPV1 4704/4885MAPT 3973/4885PGR 3890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.