SCHEMBL5454993

SCHEMBL5454993

CCCCCCCCCCNC(=S)NCCO

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.52
EPHX2 P34913 1/20 0.51
EPHX1 P07099 6/20 0.50
KDM4E B2RXH2 1/20 0.47
LMNA P02545 2/20 0.47
CASP2 P42575 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12494618 1.00 NAAA (0.52) NAAAEPHX2EPHX1KDM4ELMNA
SCHEMBL12495366 1.00 NAAA (0.52) NAAAEPHX2EPHX1KDM4ELMNA
SCHEMBL12495355 1.00 NAAA (0.52) NAAAEPHX2EPHX1KDM4ELMNA
SCHEMBL4598086 0.98 LMNA (0.49) NAAAEPHX2EPHX1KDM4ELMNA
SCHEMBL11594414 0.91 EPHX1 (0.58) NAAAEPHX2EPHX1KDM4ECASP2
SCHEMBL11593203 0.91 EPHX1 (0.58) NAAAEPHX2EPHX1KDM4ECASP2
SCHEMBL11596495 0.91 EPHX1 (0.58) NAAAEPHX2EPHX1KDM4ECASP2
SCHEMBL5081267 0.91 EPHX1 (0.58) NAAAEPHX2EPHX1KDM4ECASP2
SCHEMBL11595110 0.91 EPHX1 (0.58) NAAAEPHX2EPHX1KDM4ECASP2
SCHEMBL1273832 0.91 EPHX1 (0.58) NAAAEPHX2EPHX1KDM4ECASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed