Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12495366 | 0.98 | NAAA (0.52) | LMNAEPHX2NAAAEPHX1KDM4E | |
| SCHEMBL5454993 | 0.98 | NAAA (0.52) | LMNAEPHX2NAAAEPHX1KDM4E | |
| SCHEMBL12494618 | 0.98 | NAAA (0.52) | LMNAEPHX2NAAAEPHX1KDM4E | |
| SCHEMBL12495355 | 0.98 | NAAA (0.52) | LMNAEPHX2NAAAEPHX1KDM4E | |
| SCHEMBL462123 | 0.91 | EPHX2 (0.55) | LMNAEPHX2EPHX1KDM4EMEN1 | |
| SCHEMBL11593203 | 0.88 | EPHX1 (0.58) | EPHX2NAAAEPHX1KDM4EMEN1 | |
| SCHEMBL8979287 | 0.88 | EPHX1 (0.58) | EPHX2NAAAEPHX1KDM4EMEN1 | |
| SCHEMBL11596219 | 0.88 | EPHX1 (0.58) | EPHX2NAAAEPHX1KDM4EMEN1 | |
| SCHEMBL11595110 | 0.88 | EPHX1 (0.58) | EPHX2NAAAEPHX1KDM4EMEN1 | |
| SCHEMBL11594937 | 0.88 | EPHX1 (0.58) | EPHX2NAAAEPHX1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653259-B2 | Process for synthesizing heterocyclic compounds | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2014-02-18 | — | — | US | disclosed |
| US-20080146797-A1 | PROCESS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-06-19 | — | — | US | disclosed |
| US-20040242560-A1 | Process for synthesizing heterocyclic compounds | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
| EP-0439069-A2 | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1991-07-31 | — | — | EP | disclosed |
| US-4361639-A | SILVER IMAGE, INK RECEPTIVE AREAS | MITSUBISHI PAPER MILLS, LTD. (JP) | 1982-11-30 | — | — | US | disclosed |
| US-3969532-A | 1-Aryl-3-(2-hydroxyethyl) thioureas for treating depression | THE DOW CHEMICAL COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3969532-A | 1-Aryl-3-(2-hydroxyethyl) thioureas for treating depression | THE DOW CHEMICAL COMPANY (US) | 1976-07-13 | — | — | US | disclosed |
| US-3950538-A | Anti-inflammatory methods utilizing certain thioureas | THE DOW CHEMICAL COMPANY (US) | 1976-04-13 | — | — | US | disclosed |
| US-3950538-A | Anti-inflammatory methods utilizing certain thioureas | THE DOW CHEMICAL COMPANY (US) | 1976-04-13 | — | — | US | disclosed |
| US-3891769-A | Psychotherapeutic methods employing thioureas | DOW CHEMICAL CO | 1975-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146797-A1 | PROCESS FOR SYNTHESIZING HETEROCYCLIC COMPOUNDS | TST, NISCH, CLIC4 | LMNA 4395/4885EPHX2 1958/4885NAAA 1266/4885 |
| US-20040242560-A1 | Process for synthesizing heterocyclic compounds | TST, NISCH, CLIC4 | LMNA 4220/4885EPHX2 2327/4885NAAA 1435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.