SCHEMBL5455067

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5449741	0.90	ADORA2A (0.50)	ADORA2AADORA1ADORA3ADORA2BPTGDR2
	SCHEMBL5456361	0.88	ADORA2A (0.55)	ADORA2AADORA1ADORA3ADORA2BPTGDR2
	SCHEMBL5448759	0.83	ADORA2A (0.50)	ADORA2AADORA1ADORA3ADORA2BPTGDR2
	SCHEMBL5456365	0.78	ADORA1 (0.56)	ADORA2AADORA1ADORA3ADORA2BMAPK14
	SCHEMBL5450214	0.74	ADORA1 (0.61)	ADORA2AADORA1ADORA3ADORA2BMAPK14
	SCHEMBL5461691	0.74	ADORA1 (0.69)	ADORA2AADORA1ADORA3ADORA2BFYN
	SCHEMBL5451867	0.74	ADORA1 (0.48)	ADORA2AADORA1ADORA3ADORA2BMAPK13
	SCHEMBL5448826	0.73	ADORA1 (0.53)	ADORA2AADORA1ADORA3ADORA2BMAPK13
	SCHEMBL5447978	0.72	ADORA1 (0.69)	ADORA2AADORA1ADORA3ADORA2BMAPK13
	SCHEMBL5451373	0.72	ADORA1 (0.53)	ADORA2AADORA1ADORA3ADORA2BFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.