Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | PRMT5 | O14744 | 9/20 | 0.57 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453669 | 0.90 | PRMT5 (0.47) | ALDH1A1KDM4ETHRBPRMT5WDR77 | |
| SCHEMBL5454530 | 0.87 | DRD2 (0.58) | ALDH1A1KDM4ETHRBPRMT5WDR77 | |
| SCHEMBL5451346 | 0.85 | MEN1 (0.44) | ALDH1A1KDM4ETHRBPRMT5WDR77 | |
| SCHEMBL5454266 | 0.85 | MEN1 (0.44) | ALDH1A1KDM4ETHRBPRMT5WDR77 | |
| SCHEMBL5447833 | 0.84 | ALDH1A1 (0.65) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL5451682 | 0.83 | ALDH1A1 (0.64) | ALDH1A1KDM4ETHRBMEN1KMT2A | |
| SCHEMBL5449773 | 0.82 | PRMT5 (0.49) | ALDH1A1KDM4EPRMT5WDR77MEN1 | |
| SCHEMBL5456538 | 0.81 | NPC1 (0.67) | ALDH1A1PRMT5WDR77MEN1KMT2A | |
| SCHEMBL5784661 | 0.79 | MEN1 (0.65) | ALDH1A1KDM4ETHRBPRMT5WDR77 | |
| SCHEMBL5458947 | 0.78 | TMEM97 (0.47) | ALDH1A1KDM4EPRMT5WDR77MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | IONIX PHARMACEUTICALS LIMITED (GB) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043024-A1 | Azacyclic compounds as inhibitors of sensory neurone specific channels | SCN1B, SCN1A, SCN10A | ALDH1A1 489/4885KDM4E 1446/4885THRB 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.