Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.80 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.70 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.70 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522981 | 0.89 | ALDH1A1 (0.77) | ALDH1A1ALOX12MAPTLMNANPSR1 | |
| SCHEMBL11163778 | 0.89 | ALDH1A1 (0.65) | ALDH1A1ALOX12MAPTLMNANPSR1 | |
| SCHEMBL3059371 | 0.86 | ALDH1A1 (0.74) | ALDH1A1ALOX12MAPTLMNANPSR1 | |
| SCHEMBL6170575 | 0.84 | POLB (0.67) | ALDH1A1ALOX12MAPTLMNAMEN1 | |
| SCHEMBL30008296 | 0.84 | POLB (0.67) | ALDH1A1ALOX12MAPTLMNAMEN1 | |
| SCHEMBL6118209 | 0.84 | EPHX1 (0.78) | ALDH1A1ALOX12MAPTLMNANPSR1 | |
| SCHEMBL14096634 | 0.82 | ALDH1A1 (0.67) | ALDH1A1ALOX12MAPTLMNANPSR1 | |
| SCHEMBL9232517 | 0.81 | EPHX2 (0.60) | ALDH1A1ALOX12MAPTLMNANPSR1 | |
| SCHEMBL28169922 | 0.81 | SMN1; SMN2 (0.59) | ALDH1A1ALOX12MAPTLMNANPSR1 | |
| SCHEMBL9453927 | 0.81 | ALDH1A1 (0.67) | ALDH1A1ALOX12MAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | RNASE1, SARS1, EIF2AK2 | ALDH1A1 2930/4885ALOX12 2196/4885MAPT 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.