SCHEMBL30008296

SCHEMBL30008296

O=C(Nc1ccccc1C(F)(F)F)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.67
HDAC1 Q13547 2/20 0.66
HDAC8 Q9BY41 1/20 0.66
HDAC6 Q9UBN7 1/20 0.66
SMN1; SMN2 Q16637 2/20 0.62
MDM4 O15151 1/20 0.61
TP53 P04637 1/20 0.61
KCNK3 O14649 1/20 0.57
KCNK9 Q9NPC2 1/20 0.57
ALDH1A1 P00352 2/20 0.57
GAA P10253 2/20 0.57
LMNA P02545 2/20 0.57
MAPT P10636 2/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
ALOX12 P18054 1/20 0.57
KDM4E B2RXH2 1/20 0.56
HDAC3 O15379 1/20 0.56
MAPK1 P28482 1/20 0.56
HDAC2 Q92769 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6170575 1.00 POLB (0.67) POLBHDAC1HDAC8HDAC6SMN1; SMN2
SCHEMBL28169922 0.92 SMN1; SMN2 (0.59) POLBHDAC1HDAC8HDAC6SMN1; SMN2
SCHEMBL29768498 0.88 SMN1; SMN2 (0.61) POLBHDAC1HDAC8HDAC6SMN1; SMN2
SCHEMBL9188407 0.88 SMN1; SMN2 (0.61) POLBHDAC1HDAC8HDAC6SMN1; SMN2
SCHEMBL2307853 0.87 SMN1; SMN2 (0.60) POLBHDAC1HDAC8HDAC6SMN1; SMN2
SCHEMBL28634418 0.87 ALDH1A1 (0.75) HDAC1HDAC8HDAC6SMN1; SMN2TP53
SCHEMBL5490486 0.85 TAS2R14 (0.59) POLBHDAC1HDAC8HDAC6SMN1; SMN2
SCHEMBL5455469 0.84 ALDH1A1 (0.80) SMN1; SMN2TP53ALDH1A1GAALMNA
SCHEMBL28633823 0.84 PTGS1 (0.72) HDAC1HDAC8HDAC6TP53KCNK3
SCHEMBL30136206 0.84 PTGS1 (0.72) HDAC1HDAC8HDAC6TP53KCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121824345-A Synthesis process of chlorantraniliprole fluorobenzene bisamide 广东劲度生物科技有限公司 2026-04-10 CN disclosed
CN-113445066-B Method for electrochemically synthesizing ortho-trifluoromethyl substituted aniline by using continuous flow 南京先进生物材料与过程装备研究院有限公司 2022-12-20 CN disclosed
CN-112707835-B Bromination method of m-diamide compound 长沙嘉桥生物科技有限公司 2022-10-21 CN disclosed