SCHEMBL5455495

SCHEMBL5455495

Cc1ccccc1C(=O)NC(=S)Nc1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.72
MAPT P10636 5/20 0.72
KMT2A Q03164 3/20 0.72
HTT P42858 2/20 0.72
MEN1 O00255 1/20 0.72
KDM4E B2RXH2 2/20 0.71
POLB P06746 2/20 0.71
HPGD P15428 1/20 0.70
NPC1 O15118 2/20 0.69
RAB9A P51151 2/20 0.69
L3MBTL1 Q9Y468 1/20 0.69
ALOX12 P18054 4/20 0.67
NPSR1 Q6W5P4 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.66
EPHX1 P07099 1/20 0.63
SIRT2 Q8IXJ6 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5448102 0.91 ALDH1A1 (0.68) ALDH1A1MAPTKMT2AHTTMEN1
Hydrochloric Acid SCHEMBL3717639 0.87 ALDH1A1 (0.64) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL13453772 0.86 ALDH1A1 (0.67) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL5445679 0.86 ALDH1A1 (0.62) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL13454579 0.84 ALDH1A1 (0.69) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL14825211 0.84 ALDH1A1 (0.73) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL5452725 0.84 ALDH1A1 (0.73) ALDH1A1MAPTKMT2AHTTMEN1
Hydrochloric Acid SCHEMBL3717635 0.84 ALDH1A1 (0.62) ALDH1A1MAPTKMT2AHTTMEN1
SCHEMBL18606689 0.83 CA1 (0.73) ALDH1A1MAPTKMT2AHTTHPGD
SCHEMBL28196235 0.83 HPGD (0.74) ALDH1A1MAPTKMT2AHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101129295-B There is the binary initiator system of good storage stability and especially suitable for acidic system HERAEUS KULZER GMBH (DE) 2016-02-10 CN disclosed
CN-101129295-A 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems HERAEUS KULZER GMBH (DE) 2008-02-27 CN disclosed
US-20070040151-A1 Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems HERAEUS KULZER GMBH (DE) 2007-02-22 US disclosed