Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135787 | 0.86 | SMN1; SMN2 (0.60) | ALDH1A1MAPTNPSR1SMN1; SMN2HTT | |
| SCHEMBL5448102 | 0.86 | ALDH1A1 (0.68) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 | |
| SCHEMBL21652185 | 0.86 | SMN1; SMN2 (0.74) | ALDH1A1MAPTNPSR1SMN1; SMN2HTT | |
| SCHEMBL5455495 | 0.86 | ALDH1A1 (0.72) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3717639 | 0.82 | ALDH1A1 (0.64) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 | |
| SCHEMBL15257990 | 0.82 | SMN1; SMN2 (0.82) | ALDH1A1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL21588735 | 0.81 | ALDH1A1 (0.65) | ALDH1A1NPSR1SMN1; SMN2HTTKMT2A | |
| SCHEMBL12067341 | 0.81 | SIRT1 (0.71) | ALDH1A1MAPTNPSR1SMN1; SMN2SIRT2 | |
| SCHEMBL2349003 | 0.80 | EPHX1 (0.73) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3717635 | 0.80 | ALDH1A1 (0.62) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |