Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455495 | 0.91 | ALDH1A1 (0.72) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3717639 | 0.87 | ALDH1A1 (0.64) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 | |
| SCHEMBL5445679 | 0.86 | ALDH1A1 (0.62) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3717635 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 | |
| SCHEMBL13454579 | 0.85 | ALDH1A1 (0.69) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 | |
| SCHEMBL3684485 | 0.84 | HPGD (0.79) | ALDH1A1MAPTNPSR1SMN1; SMN2HTT | |
| SCHEMBL29519361 | 0.84 | HPGD (0.79) | ALDH1A1MAPTNPSR1SMN1; SMN2HTT | |
| SCHEMBL18606689 | 0.84 | CA1 (0.73) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 | |
| SCHEMBL5457898 | 0.81 | ALDH1A1 (0.81) | ALDH1A1MAPTNPSR1SMN1; SMN2KMT2A | |
| SCHEMBL5456687 | 0.81 | ALDH1A1 (0.67) | ALDH1A1MAPTALOX12NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| WO-2011022393-A2 | PHOSPHATIDYLCHOLINE TRANSFER PROTEIN INHIBITORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-02-24 | — | — | WO | disclosed |
| CN-101129295-A | 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems | HERAEUS KULZER GMBH (DE) | 2008-02-27 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |