Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15484217 | 0.82 | KDM4E (0.63) | LMNAGAAKMT2AMEN1MAPT | |
| SCHEMBL10099725 | 0.80 | GAA (0.83) | LMNAGAAKMT2AMEN1POLB | |
| SCHEMBL25206832 | 0.77 | LMNA (0.59) | LMNAGAAKMT2AMEN1POLB | |
| SCHEMBL4130947 | 0.74 | RAPGEF4 (0.73) | — | |
| SCHEMBL16786363 | 0.74 | KMT2A (0.59) | LMNAGAAKMT2AMEN1POLB | |
| SCHEMBL11511410 | 0.72 | ALDH1A1 (0.59) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL10710275 | 0.72 | NOX1 (0.85) | LMNAGAAKMT2AMEN1POLB | |
| SCHEMBL6302055 | 0.72 | GAA (0.64) | LMNAGAAKMT2AMEN1POLB | |
| SCHEMBL18031169 | 0.72 | GAA (1.00) | LMNAGAAKMT2AMEN1POLB | |
| SCHEMBL3285738 | 0.72 | PPIA (0.70) | LMNAGAAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |