Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.83 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | MAOA | P21397 | 2/20 | 0.72 |
| ▸ | MAOB | P27338 | 2/20 | 0.72 |
| ▸ | IDO1 | P14902 | 2/20 | 0.69 |
| ▸ | EGFR | P00533 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31388373 | 0.92 | KMT2A (0.89) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL5442089 | 0.92 | KMT2A (0.89) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL16566477 | 0.91 | KMT2A (1.00) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6816155 | 0.88 | KMT2A (0.75) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL5137359 | 0.84 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8956372 | 0.84 | MAPT (0.83) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL5455602 | 0.84 | MAPT (0.83) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7594296 | 0.82 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL11051606 | 0.81 | MAOA (0.72) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6153945 | 0.81 | IDO1 (1.00) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461821-A | Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound | FUJI PHOTO FILM CO., LTD. (JP) | 1984-07-24 | — | — | US | disclosed |