Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 11/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5458277 | 0.81 | MMP13 (0.39) | MEN1KMT2ASRC | |
| SCHEMBL4488508 | 0.79 | SRC (0.54) | S1PR5S1PR1S1PR3ALDH1A1MEN1 | |
| SCHEMBL5452631 | 0.78 | SRC (0.36) | SRC | |
| SCHEMBL5217735 | 0.78 | TSHR (0.49) | S1PR5S1PR1S1PR3ALDH1A1MEN1 | |
| SCHEMBL13818401 | 0.77 | SRC (0.49) | S1PR5S1PR1S1PR3ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL4494354 | 0.77 | TSHR (0.48) | S1PR5S1PR1S1PR3ALDH1A1MEN1 | |
| SCHEMBL4481471 | 0.68 | METAP1 (0.45) | SRC | |
| SCHEMBL13818446 | 0.68 | METAP1 (0.45) | SRC | |
| SCHEMBL16874568 | 0.68 | LMNA (0.46) | ALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL13951565 | 0.64 | TSHR (0.54) | S1PR5S1PR1ALDH1A1MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244087-A1 | 2-ALKOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244087-A1 | 2-ALKOXY-3,4,5-TRIHYDROXY-ALKYLAMIDES, PREPARATION THEREOF, COMPOSITIONS CONTAINING THEM AND USE THEREOF | HCCS, ALKBH2, ALKBH3 | S1PR5 198/4885S1PR1 575/4885S1PR3 142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.