Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061797 | 0.98 | MEN1 (0.52) | HTTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL12566375 | 0.89 | MAPT (0.43) | HTTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL13602108 | 0.86 | MEN1 (0.41) | HTTLMNAKDM4ENPC1RAB9A | |
| Iodide SCHEMBL7861647 | 0.85 | LMNA (0.47) | HTTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL18883514 | 0.83 | MEN1 (0.39) | HTTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL28596285 | 0.83 | MEN1 (0.39) | HTTLMNAKDM4ENPC1RAB9A | |
| SCHEMBL3447497 | 0.83 | ALDH1A1 (0.48) | HTTLMNASMN1; SMN2MEN1TP53 | |
| Hydrochloric Acid SCHEMBL3446376 | 0.82 | LMNA (0.47) | HTTLMNANPC1RAB9ASMN1; SMN2 | |
| Bromide SCHEMBL5683015 | 0.82 | CHKA (0.50) | HTTLMNASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL9342255 | 0.81 | CHRM2 (0.45) | HTTLMNAKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070020479-A1 | Luminescent-polymer composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-25 | — | — | US | disclosed |