Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 9/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447497 | 0.98 | ALDH1A1 (0.48) | LMNAALDH1A1CYP3A4HSD17B10CHKA | |
| Bromide SCHEMBL5683015 | 0.97 | CHKA (0.50) | LMNAALDH1A1CYP3A4HSD17B10CHKA | |
| Hydrochloric Acid SCHEMBL3446376 | 0.97 | LMNA (0.47) | LMNAALDH1A1CYP3A4HSD17B10CHKA | |
| Bromide SCHEMBL6795666 | 0.95 | CHKA (0.49) | LMNAALDH1A1CYP3A4HSD17B10CHKA | |
| Iodide SCHEMBL5455905 | 0.85 | HTT (0.53) | LMNAALDH1A1CYP3A4HSD17B10HTT | |
| SCHEMBL13061797 | 0.83 | MEN1 (0.52) | LMNAALDH1A1CYP3A4HSD17B10HTT | |
| SCHEMBL9834890 | 0.83 | CHRM2 (0.40) | LMNAALDH1A1CYP3A4HSD17B10CHKA | |
| Bromide SCHEMBL9328651 | 0.82 | CHRM2 (0.42) | LMNAALDH1A1CYP3A4HSD17B10CHKA | |
| Hydrochloric Acid SCHEMBL6687261 | 0.82 | CHRM2 (0.40) | LMNAALDH1A1CYP3A4HSD17B10HTT | |
| SCHEMBL13690222 | 0.81 | LMNA (0.47) | LMNAALDH1A1CYP3A4HSD17B10CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204386-B1 | PYRIDINIUM COMPOUND | ARTEVA NORTH AMERICA S.A.R.L. (CH) | 2001-03-20 | — | — | US | disclosed |