Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 3/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 3/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27555287 | 1.00 | DPP4 (0.47) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL13016671 | 0.93 | DPP4 (0.42) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL30019279 | 0.88 | DPP4 (0.53) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL28412557 | 0.88 | DPP4 (0.53) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL19439391 | 0.83 | ANPEP (0.42) | DPP4DPP8DPP9ANPEPDNPEP | |
| SCHEMBL9572303 | 0.83 | SLC7A5 (0.47) | ANPEPDNPEPTAS1R3TAS1R1SLC7A5 | |
| SCHEMBL14269010 | 0.80 | TAS1R3 (0.40) | ANPEPDNPEPTAS1R3TAS1R1AURKA | |
| SCHEMBL13035554 | 0.80 | TAS1R3 (0.40) | ANPEPDNPEPTAS1R3TAS1R1AURKA | |
| SCHEMBL13034816 | 0.80 | TAS1R3 (0.40) | ANPEPDNPEPTAS1R3TAS1R1AURKA | |
| SCHEMBL10079223 | 0.78 | MMP1 (0.40) | TAS1R3TAS1R1MMECYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293560-A1 | Compounds and compositions | ABELL ANDREW D | 2007-12-20 | — | — | US | disclosed |
| US-20070293560-A1 | Compounds and compositions | ABELL ANDREW D | 2007-12-20 | — | — | US | disclosed |
| US-20070293560-A1 | Compounds and compositions | ABELL ANDREW D | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293560-A1 | Compounds and compositions | CAPN1, CAPN2, CAPN9 | DPP4 452/4885DPP8 499/4885DPP9 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.