Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456087 | 1.00 | SLC6A9 (0.45) | SLC6A9OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5454642 | 1.00 | SLC6A9 (0.45) | SLC6A9OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9363615 | 0.82 | OPRD1 (0.44) | SLC6A9OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9363609 | 0.82 | OPRD1 (0.44) | SLC6A9OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5456638 | 0.82 | OPRD1 (0.44) | SLC6A9OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL4589194 | 0.82 | OPRD1 (0.44) | SLC6A9OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5456644 | 0.82 | OPRD1 (0.44) | SLC6A9OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL9760922 | 0.81 | OPRD1 (0.43) | SLC6A9OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL9760915 | 0.81 | OPRD1 (0.43) | SLC6A9OPRM1OPRD1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL9760911 | 0.81 | OPRD1 (0.43) | SLC6A9OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066587-A1 | Substituted azetidine compounds, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE S.A (ES) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066587-A1 | Substituted azetidine compounds, their preparation and use as medicaments | AZI2, NISCH, QDPR | SLC6A9 1388/4885OPRM1 829/4885OPRD1 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.