Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | EED | O75530 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088880 | 0.73 | PIK3CD (0.45) | DRD2KCNH2PIK3CDPIK3R2PIK3CG | |
| SCHEMBL28778952 | 0.69 | DRD2 (0.41) | DRD2CCR2KCNH2IL1BP2RX7 | |
| Hydrochloric Acid SCHEMBL11229179 | 0.67 | HPGD (0.57) | — | |
| SCHEMBL11219884 | 0.66 | MEN1 (0.51) | DRD2CCR2KCNH2FEN1 | |
| SCHEMBL27645127 | 0.65 | EED (0.57) | KCNH2EED | |
| SCHEMBL11226159 | 0.64 | DRD2 (0.48) | DRD2KCNH2FEN1 | |
| SCHEMBL11230368 | 0.64 | DRD2 (0.48) | DRD2CCR2KCNH2FEN1 | |
| SCHEMBL25881868 | 0.63 | MEN1 (0.47) | DRD2CCR2KCNH2PARP1PIK3CD | |
| SCHEMBL25881886 | 0.63 | MEN1 (0.47) | DRD2CCR2KCNH2PARP1PIK3CD | |
| SCHEMBL5473385 | 0.63 | PSMB8 (0.42) | DRD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | DRD2 4327/4885CCR2 3039/4885KCNH2 2082/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.