Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 4/20 | 0.39 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | PRPS1 | P60891 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 3/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088880 | 0.75 | PIK3CD (0.45) | DRD2NPY1RACP1PIK3CDPIK3R2 | |
| SCHEMBL5456475 | 0.69 | DRD2 (0.41) | DRD2PIK3CDPIK3R2PIK3CGIL1B | |
| SCHEMBL17186937 | 0.69 | PRMT5 (0.40) | — | |
| SCHEMBL5000469 | 0.67 | PRMT5 (0.41) | PRPS1 | |
| SCHEMBL27645127 | 0.65 | EED (0.57) | KCNH2EED | |
| SCHEMBL2544813 | 0.63 | LMNA (0.57) | NPY1RBRD4 | |
| SCHEMBL8566833 | 0.62 | PRMT5 (0.41) | PARP1 | |
| SCHEMBL8244003 | 0.60 | DRD2 (0.40) | DRD2PARP1EED | |
| SCHEMBL7815243 | 0.60 | PRMT5 (0.47) | DRD2PRPS1PARP1 | |
| SCHEMBL19190735 | 0.60 | PRMT5 (0.45) | PIK3CDPIK3R2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101405000-A | 2-imino-benzimidazoles | ABBOTT LAB (US) | 2009-04-08 | — | — | CN | disclosed |