Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3063620 | 0.80 | ALDH1A1 (0.76) | MEN1KMT2AALOX12ALDH1A1GAA | |
| SCHEMBL5448347 | 0.79 | GAA (0.64) | MEN1KMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9461871 | 0.75 | LMNA (0.50) | SMN1; SMN2ALDH1A1GAAMAPTLMNA | |
| SCHEMBL6347544 | 0.75 | MEN1 (0.60) | MEN1KMT2AALOX12HPGDSMN1; SMN2 | |
| SCHEMBL17794373 | 0.75 | GAA (0.67) | MEN1KMT2AALOX12HPGDSMN1; SMN2 | |
| SCHEMBL6560123 | 0.74 | CHRM2 (0.52) | MEN1KMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL28542586 | 0.73 | MEN1 (1.00) | MEN1KMT2AALOX12HPGDSMN1; SMN2 | |
| SCHEMBL325076 | 0.73 | ALDH1A1 (0.62) | MEN1KMT2ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11598264 | 0.72 | ALDH1A1 (0.77) | KMT2ASMN1; SMN2ALDH1A1GAAMAPT | |
| SCHEMBL24169100 | 0.71 | LMNA (0.88) | MEN1KMT2AALOX12HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |