Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9461871 | 0.85 | LMNA (0.50) | GAAKDM4ELMNAPOLBMAPT | |
| SCHEMBL10789222 | 0.84 | LMNA (0.56) | GAAKDM4ELMNAMAPTHTT | |
| SCHEMBL2236429 | 0.84 | GAA (0.66) | GAAKDM4ELMNAMAPTHTT | |
| SCHEMBL10787178 | 0.83 | MAPT (0.74) | GAAKDM4ELMNAMAPTSMN1; SMN2 | |
| SCHEMBL8611437 | 0.82 | GAA (0.64) | GAAKDM4ELMNAMAPTHTT | |
| SCHEMBL1647857 | 0.81 | ALDH1A1 (0.69) | GAAKDM4ELMNAPOLBMAPT | |
| SCHEMBL8956298 | 0.81 | LMNA (0.74) | GAAKDM4ELMNAPOLBMAPT | |
| SCHEMBL5456513 | 0.79 | MEN1 (0.58) | GAALMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL28820821 | 0.79 | LMNA (0.70) | GAAKDM4ELMNAPOLBMAPT | |
| SCHEMBL2856729 | 0.79 | GAA (0.59) | GAAKDM4ELMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |