SCHEMBL5456637

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5466558	0.89	RB1 (0.62)	RB1CDC42CYP2D6KCNH2MAPT
	SCHEMBL5456543	0.87	RB1 (0.60)	RB1CDC42CYP2D6KCNH2MAPT
	SCHEMBL5458904	0.85	RB1 (0.64)	RB1CDC42CYP2D6KCNH2MAPT
	SCHEMBL4196380	0.84	RB1 (1.00)	RB1CDC42CYP2D6KCNH2MAPT
	Hydrochloric Acid SCHEMBL4162233	0.83	RB1 (1.00)	RB1CDC42CYP2D6KCNH2MAPT
	SCHEMBL5475990	0.82	RB1 (0.54)	RB1CDC42CYP2D6MAPTALOX15
	SCHEMBL5394699	0.82	RB1 (0.69)	RB1CDC42CYP2D6KCNH2MAPT
	SCHEMBL14361410	0.82	RB1 (0.69)	RB1CDC42CYP2D6KCNH2MAPT
	SCHEMBL5456549	0.82	ALOX15 (0.70)	RB1MAPTALOX15SMN1; SMN2MEN1
	SCHEMBL5456640	0.82	RB1 (0.69)	RB1MAPTALOX15SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.