SCHEMBL5456640

SCHEMBL5456640

Fc1ccc2[nH]c3c(c2c1)CCCC3NC1CCCCC1

nearest known ligand 0.69

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RB1 P06400 6/20 0.69
BRD3 Q15059 12/20 0.64
HTR2A P28223 1/20 0.54
HTR2C P28335 1/20 0.54
MEN1 O00255 1/20 0.51
GLA P06280 1/20 0.51
MAPT P10636 1/20 0.51
ALOX15 P16050 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5468093 0.86 RB1 (0.57) RB1BRD3MEN1GLAMAPT
SCHEMBL14361410 0.85 RB1 (0.69) RB1BRD3MEN1GLAMAPT
SCHEMBL5456549 0.85 ALOX15 (0.70) RB1HTR2AHTR2CMEN1GLA
SCHEMBL4163723 0.85 RB1 (0.69) RB1BRD3MEN1GLAMAPT
SCHEMBL5394699 0.85 RB1 (0.69) RB1BRD3MEN1GLAMAPT
SCHEMBL21998619 0.84 RB1 (0.68) RB1BRD3MEN1GLAMAPT
SCHEMBL5445881 0.82 RB1 (0.53) RB1BRD3HTR2AHTR2CMEN1
SCHEMBL15278256 0.82 MAPT (0.74) RB1BRD3HTR2AHTR2CMEN1
SCHEMBL5456637 0.82 RB1 (0.72) RB1BRD3MEN1GLAMAPT
SCHEMBL4196380 0.82 RB1 (1.00) RB1BRD3MEN1GLAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070276009-A1 Compositions and Methods for Viral Inhibition CHIRON CORPORATION 2007-11-29 US disclosed
US-20070276009-A1 Compositions and Methods for Viral Inhibition CHIRON CORPORATION 2007-11-29 US disclosed
US-20070276009-A1 Compositions and Methods for Viral Inhibition CHIRON CORPORATION 2007-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070276009-A1 Compositions and Methods for Viral Inhibition MAVS, SARS1, ZC3HAV1 RB1 1821/4885BRD3 529/4885HTR2A 3924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.